Why is a person with klinefelter syndrome male

Starting treatment early can prevent some of the symptoms. One of the main treatments is testosterone replacement therapy. Taking testosterone around the time of puberty will trigger the development of male characteristics that normally happen at puberty, such as:.

Learn more: Hormone replacement therapy for men ». You can take testosterone as a pill, patch, or cream. Or you can get it by injection every two to three weeks. If you have a low sperm count, a procedure called intracytoplasmic sperm extraction with intracytoplasmic sperm injection TESE-ICSI removes sperm directly from your testicle and injects it into an egg to increase the chances of pregnancy.

It can be hard to live with Klinefelter syndrome. Boys might be embarrassed about the lack of changes in their body during puberty. A therapist or counselor can help you manage any depression, low self-esteem, or other emotional issues that stem from this condition. You might also look for a support group, where you can talk with other men who have this condition.

You can find support groups through your doctor or on the internet. Children with Klinefelter syndrome often need extra help in school. Contact your local school district to find out about special programs for kids with disabilities. Many boys with Klinefelter syndrome have more trouble interacting socially than their peers.

An occupational or behavioral therapist can help them learn social skills. You and your doctor will need to watch out for conditions that are more common in men with Klinefelter syndrome, including:. According to research , Klinefelter syndrome can shorten your life expectancy up to two years. However, you can still live a long, full life with this condition. The earlier you get treatment, the better your outlook will be.

Mosaic Down syndrome is a rare, less severe form of Down syndrome. We explain the condition, its cause, symptoms, and how to diagnose it. Down syndrome is the most common genetic condition in the United States. Curly hair is determined by factors you inherit from your biological parents.

About Klinefelter syndrome. National Human Genome Research Institute. Klinefelter syndrome 47,XXY. Merck Manual Professional Version. Klinefelter syndrome KS. Genetic and Rare Diseases Information Center. Bearelly P, et al. Recent advances in managing and understanding Klinefelter syndrome.

Ferri FF. In: Ferri's Clinical Advisor Elsevier; Hererra Lizarazo A, et al. Endocrine aspects of Klinefelter syndrome. Current Opinion in Endocrinology, Diabetes and Obesity. Wick MJ expert opinion. Mayo Clinic. Deng C, et al. Clinical application of noninvasive prenatal screening for sex chromosome aneuploidies in 50, pregnancies: Initial experience in a Chinese hospital. Scientific Reports. However, because of nondisjunction, an egg cell or a sperm cell can also end up with an extra copy of the X chromosome.

If an egg cell with an extra X chromosome XX is fertilized by a sperm cell with one Y chromosome, the resulting child will have Klinefelter syndrome.

Similarly, if a sperm cell with both an X chromosome and a Y chromosome XY fertilizes an egg cell with a single X chromosome, the resulting child will have Klinefelter syndrome.

It occurs as a random error during cell division early in fetal development. As a result, some of the body's cells have the usual one X chromosome and one Y chromosome 46,XY , and other cells have an extra copy of the X chromosome 47,XXY.

Genetics Home Reference has merged with MedlinePlus. Learn more. The information on this site should not be used as a substitute for professional medical care or advice. Contact a health care provider if you have questions about your health. Klinefelter syndrome. From Genetics Home Reference.

Description Klinefelter syndrome is a chromosomal condition in boys and men that can affect physical and intellectual development. Frequency Klinefelter syndrome affects about 1 in newborn boys. Causes Klinefelter syndrome is a sex chromosome disorder in boys and men that results from the presence of an extra X chromosome in cells. Learn more about the chromosome associated with Klinefelter syndrome x chromosome. Inheritance Klinefelter syndrome is not inherited; the addition of an extra X chromosome occurs during the formation of reproductive cells eggs or sperm in one of an affected person's parents.

Research Studies from ClinicalTrials. The cognitive phenotype in Klinefelter syndrome: a review of the literature including genetic and hormonal factors. Dev Disabil Res Rev. Adv Pediatr. Chromosomal variants in klinefelter syndrome.

Sex Dev. Epub Apr Klinefelter syndrome: clinical and molecular aspects. Expert Rev Mol Diagn. Clinical review: Klinefelter syndrome--a clinical update. J Clin Endocrinol Metab.

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